Copper Tripeptide-1 (GHK-Cu) is a naturally occurring copper-binding peptide that plays a fundamental role in tissue repair and regeneration through multiple pathways:
Extracellular Matrix Remodeling:
Stem Cell Activation & Cellular Communication:
Anti-Inflammatory & Antioxidant Effects:
12-week study on 60 volunteers (40-65 years) using 5 ppm Copper Tripeptide-1:
Excellent safety profile with over 30 years of clinical use. Non-irritating, non-sensitizing, suitable for sensitive skin.
Stable in pH 5.0-7.5. Avoid strong chelating agents (EDTA), high metal concentrations, and strong reducing agents.
Protect from light and oxidation. Ideal for aqueous systems and emulsions.
Concentration: 1-10 ppm (0.0001%-0.001%) in final formulations.
Optimal Dose: 5 ppm for clinically proven regenerative effects.







A: The clinically proven optimal dose is 5 ppm (0.0005%), although it is effective within a range of 1-10 ppm.
A: Yes, it has an excellent safety profile with over 30 years of clinical history. It is non-irritating and suitable for sensitive skin types.
A: Avoid using strong chelating agents like EDTA, high concentrations of other metals, and strong reducing agents, as these can affect the stability of the copper peptide.
A: Clinical trials show up to a 42% improvement in skin smoothness and roughness, alongside significant reductions in fine lines and wrinkles.
A: Yes, the product does not contain any animal-derived components and is considered vegan-friendly.
A: It is recommended to protect the final products from light and oxidation, ideally in a closed container in a cool, dry place.