Acetyl Tetrapeptide-2 is a biomimetic peptide specifically designed to target and mitigate neurogenic inflammation, a key driver of facial redness and sensitivity, particularly in conditions like rosacea.
Human clinical studies on Rosacea & Redness-Prone Skin (4-8 weeks) showed:
Over 80% of participants agreed their skin felt "more calm," "less reactive," and "soothed" after continued use.


Non-irritating and non-sensitizing. Specifically designed for fragile, reactive skin and suitable for long-term use.
Synergistic Combinations:
Works effectively with Niacinamide (barrier strength), Centella Asiatica (anti-inflammatory), and Ceramides (lipid repair).
Recommended Concentration: 2 - 6 ppm (0.0002% - 0.0006%) in the final product. Effective at very low concentrations.
Applications:
Targets Root Cause
Clinically Proven
Rapid & Lasting Calm
Exceptionally Safe
Barrier-Supportive
Marketing Synergy
Storage
Dry place, Room temperature
Animal Testing
Not animal tested
Vegan
No animal-derived components
GMO
No data available
A: It acts as a "neuro-soother" that specifically targets neurological signals causing redness and irritation, effectively managing reactive and rosacea-prone skin.
A: It inhibits the release of Substance P from sensory neurons, which reduces neurogenic inflammation and prevents the widening of blood vessels.
A: It is effective at very low concentrations, with a recommended usage of 2 to 6 ppm (0.0002% - 0.0006%).
A: Yes, it is ideal for post-procedure recovery serums to minimize redness and discomfort following treatments like chemical peels or lasers.
A: Absolutely. It is non-irritating, non-sensitizing, and highly targeted, making it safe for daily maintenance of fragile skin.
A: Yes, it shows excellent synergy with Niacinamide, Ceramides, and botanical extracts like Centella Asiatica for comprehensive barrier support.