Buy Dipetide Diaminobutyroyl Benzylamide Diacetate A Comprehensive Review of Its Cosmetic Properties Manufacturers, Companies

Products Name   Dipetide diaminobutyroyl Benzylamide diacetate
CAS No  823202-99-9
INCI Name  Acetyl Dipeptide-1 Cetyl Ester
Specification  ≥98% (HPLC)
Molecular Weight  483.6 g/mol
Chemical Formula  C₂₄H₄₁N₅O₅
Appearance  White to off-white fine powder
Solubility  Soluble in oils and organic solvents. Low solubility in water.

Product Description

Product Description

Acetyl Dipeptide-1 Cetyl Ester

Acetyl Dipeptide-1 Cetyl Ester is a renowned synthetic peptide that acts as a topical alternative to injectable neurotoxins. Its mechanism is designed to reduce the appearance of expression lines by modulating neuromuscular signals.

Mechanism of Action (MOA)

Inhibition of Acetylcholine Release: Competitively inhibits the interaction between the SNARE protein complex and acetylcholine-containing vesicles, leading to a partial and reversible reduction in neurotransmitter release.

Reduction of Muscle Contractions: Facial muscles responsible for frown lines and crow's feet are softened and relaxed due to reduced signaling.

Reversible & Non-Toxic Action: Unlike injectable neurotoxins, this peptide does not cause permanent proteolysis. Its effect is temporary, safe for long-term use, and enhanced by a cetyl ester group for better skin penetration.

In Vitro Efficacy & Clinical Results

  • SNARE Complex Inhibition: Dose-dependent reduction in acetylcholine release demonstrated in neuronal cell lines.
  • Muscle Contraction Reduction: Significant decrease in contraction frequency in human skin models.
  • Wrinkle Depth Reduction: Clinical studies showed up to 27% reduction in crow's feet depth after 28 days of twice-daily application.
  • Global Improvement: Noticeable improvement in wrinkle scores observed as early as 15-30 days.

Safety & Compatibility

Safety Profile
Compatibility

Safety Profile

Excellent safety profile for topical use. Non-irritating, non-sensitizing, and acts locally without systemic effects.

Compatibility

Synergistic Combinations: Works well with Palmitoyl Tripeptide-38, Hyaluronic Acid, Vitamin C, E, and Ceramides.

Formulation Stability: Stable in pH range 4.0-8.0. Suitable for serums, emulsions, and gels.

Recommended Dosage & Formulations

Formulation
Usage Level: 2 - 10 ppm (0.0002% - 0.001%)

Potent even at extremely low concentrations. Ideal for:

Anti-Wrinkle Serums
Eye Contour Gels
Day/Night Creams
"Botox-like" Treatments

Summary & Key Selling Points

Botox Alternative

Topical Botox Alternative

Non-invasive, needle-free solution mimicking neurotoxin mechanisms.

Efficacy

Clinically Proven

Significant reduction in wrinkle depth, particularly in the crow's feet area.

Safety

Safe & Reversible

Temporary muscle-relaxing effect ensures high safety for continuous use.

Potency

High Potency

Effective at ppm concentrations, offering excellent cost-effectiveness.

Appeal

Consumer Appeal

Powerful "Botox in a jar" concept for needle-free clinical results.

Penetration

Enhanced Penetration

Cetyl ester group ensures effective delivery to the target site.

Storage

Storage
Dry place, room temperature

Testing

Cruelty Free
Not animal tested

Vegan

Vegan
No animal components

GMO

GMO Free
Non-GMO

Frequently Asked Questions

What is Acetyl Dipeptide-1 Cetyl Ester?
It is a synthetic lipopeptide designed to reduce muscle contractions by mimicking the effect of injectable neurotoxins, providing a "Botox-like" smoothing effect on expression lines.
How does it differ from actual Botox injections?
While Botox causes permanent proteolysis of proteins to stop contractions, this peptide works through a reversible inhibition of acetylcholine release. It is non-toxic, non-invasive, and suitable for daily topical application.
What results can I expect from clinical data?
Studies have shown a reduction in wrinkle depth by up to 27% after 28 days of use, with visible improvements in skin smoothness often appearing within 15 to 30 days.
Is it safe for long-term skincare use?
Yes, it has an excellent safety profile. It is non-irritating, non-sensitizing, and acts only locally on the skin without systemic risks.
What is the recommended usage level in formulations?
The recommended dosage is extremely low due to its high potency, typically ranging from 2 to 10 ppm (parts per million) in the final formulation.
Can this peptide be used with other active ingredients?
Yes, it is highly compatible with other anti-aging actives like Hyaluronic Acid, other peptides (e.g., Palmitoyl Tripeptide-38), Vitamin C, and Ceramides.

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