ODM The Anti-Aging Power of Alpha-Ketoglutarate Factory, Exporter

1 / 1

ODM The Anti-Aging Power of Alpha-Ketoglutarate Factory, Exporter

Products Name	Â Alpha-Ketoglutarate (AKG)
CAS No	Â 328-50-7Â
INCI Name	Â Alpha-Ketoglutaric Acid
Specification	Â â‰¥99% (HPLC), Pharmaceutical Grade
Molecular Weight	Â 146.11 g/mol
Chemical Formula	Â Câ‚…Hâ‚†Oâ‚…
Appearance	Â White crystalline powder
Solubility	Â Freely soluble in water (500 mg/mL), slightly soluble in ethanol

Send Inquiry

Product Description

Alpha-ketoglutarate (α-Ketoglutarate, often abbreviated as AKG) is a naturally occurring organic compound and a key intermediate in the Krebs cycle (citric acid cycle), a central metabolic pathway in cells. In cosmetics, it is typically used in its stabilized forms (e.g., sodium alpha-ketoglutarate or calcium alpha-ketoglutarate) to enhance solubility and stability in formulations.

Chemically, it is a five-carbon dicarboxylic acid, known for its role in energy metabolism and amino acid synthesis in the body. In skincare, its biological activity is linked to supporting cellular energy production, collagen synthesis, and antioxidant defense, making it a versatile ingredient in anti-aging and rejuvenating products.

Key Performance Indicators

Unlock the secret to cellular youth with Alpha-Ketoglutarate (AKG), a premium-grade mitochondrial nutrient clinically proven to combat skin aging at the metabolic level.

Cellular Energy Boost – Recharges aging skin's ATP production
Collagen Synthesis – Increases Type I collagen by 30% in clinical studies*
DNA Protection – Reduces oxidative damage by supporting NAD+ levels
Wound Healing – Accelerates tissue repair in post-procedure formulations

Key Benefits

Boosts collagen and elastin synthesis

Acts as a precursor for amino acids essential for collagen and elastin production, helping to improve skin firmness and reduce fine lines.

Antioxidant and anti-glycation

Neutralizes free radicals and inhibits glycation—preserving skin’s youthful texture and protecting against UV stress.

Exfoliation and skin renewal

Mildly promotes desquamation without irritation, unclogging pores and smoothing rough skin texture for sensitive skin.

Usage Guidelines

Typically used in cosmetic formulations at concentrations of 0.5%–5%.

0.5%–2%: Common in daily anti-aging or brightening products.
3%–5%: Used in targeted treatments for mature or dull skin.

Applications

Commonly used in facial creams, serums, lotions, and masks.

Skincare Products

Lotions and masks to combat dullness by enhancing cellular turnover and antioxidant defense.

Anti-Aging Products

Targeting fine lines and loss of elasticity, often paired with peptides or coenzyme Q10.

Post-Sun & Repair

Supporting skin recovery after UV exposure by aiding in cellular repair.

Storage: Dry place, room temperature.

Animal Testing: Not animal tested.

Vegan: Animal-free components.

Frequently Asked Questions

What is Alpha-Ketoglutarate (AKG) used for in skincare?

AKG is primarily used for its anti-aging properties, as it supports mitochondrial health, boosts collagen synthesis, and provides antioxidant protection.

Is AKG suitable for sensitive skin?

Yes, AKG is known for providing mild exfoliation and skin renewal without the harsh irritation often associated with stronger acids.

What is the recommended concentration for cosmetic formulations?

The typical concentration ranges from 0.5% to 5%, depending on whether it is for daily maintenance or intensive treatment.

Can AKG be paired with other active ingredients?

Absolutely. It works synergistically with hyaluronic acid, peptides, and coenzyme Q10 to enhance hydration and anti-aging results.

How does AKG support the skin's barrier?

AKG can enhance natural moisturizing factors and strengthen the stratum corneum, which improves hydration retention and reduces water loss.

Is your AKG ingredient vegan-friendly?

Yes, the product does not contain any animal-derived components and is suitable for vegan-friendly formulations.