ODM Gluconolactone Peptide Gentle PHA Exfoliator for Smooth & Bright Skin Factory, Factories

Products Name Gluconolactone Peptide
CAS No 860627-90-3
INCI Name Gluconolactone Peptide
Specification ≥98% (HPLC)
Molecular Weight 178.14 g/mol
Chemical Formula  C₆H₁₀O₆
Appearance  White to off-white crystalline powder
Solubility Water-soluble

Product Description

Product Description

Gluconolactone Peptide Analysis

MOA: Gluconolactone Peptide is a sophisticated hybrid active that combines the benefits of Polyhydroxy Acid (PHA) and peptides, offering a multi-mechanism approach to skin rejuvenation.

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Gentle Corneocyte Desquamation

The gluconolactone (a PHA) moiety functions as a gentle humectant exfoliant. It works by breaking the ionic bonds between dead corneocytes, promoting a smoother texture without compromising the skin barrier.

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Peptide-Mediated Signaling

Stimulates fibroblasts to boost Collagen & Elastin synthesis, reducing fine lines and improving skin firmness while enhancing barrier functions like ceramides and filaggrin.

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Antioxidant & Anti-Glycation

Protects skin from free radical damage and prevents protein glycation, preserving elasticity and preventing premature aging.

Scientific Efficacy Data

In Vitro Efficacy

  • Antioxidant Activity: High Oxygen Radical Absorbance Capacity (ORAC).
  • Anti-Glycation: Dose-dependent inhibition of AGEs formation.
  • Collagen Synthesis: Significant increase (>30%) in Collagen I production.
  • Gene Expression: Upregulation of COL1A1, COL3A1 and downregulation of MMP-1.

Clinical Results (8-12 Weeks)

  • Wrinkle Reduction: Significant reduction in depth and volume of fine lines.
  • Radiance: Up to 20% improvement in skin brightness and clarity.
  • Hydration: Immediate and long-term increase in moisture levels.
  • Tolerance: 95% of subjects with sensitive skin reported zero irritation.

Safety & Compatibility

Safety
pH compatibility
Formulation

Safety Profile

Excellent mildness; suitable for sensitive skin, rosacea, and eczema where traditional AHAs are not tolerated.

pH Range

Optimal effectiveness between pH 3.5 and 6.0.

Formulation

Highly compatible with various cosmetic bases; less likely to cause irritation compared to hydroquinone or arbutin.

Recommended Usage & Dosage

Usage Level: 2% - 5% in final formulations.

  • Serums: High-performance targeted treatments.
  • Moisturizers: Daily anti-aging and hydration.
  • Eye Creams: Gentle care for delicate skin.
  • Toners/Masks: Rinse-off or leave-on exfoliation.

Summary & Key Selling Points

Exfoliant
Anti-aging
Clinically proven

Next-Gen Exfoliation

AHA benefits without the irritation.

Multi-Modal Aging

Hydration, Collagen, and Antioxidant protection in one.

Skin Resilience

Strengthens the barrier against environmental aggressors.

Storage
Storage: Closed container, dry place, room temperature.
Cruelty Free
Animal Testing: Not animal tested.
Vegan
Vegan: No animal-derived components.

Frequently Asked Questions

Q1: What makes Gluconolactone Peptide different from standard AHAs?

Unlike AHAs like Glycolic Acid, the Gluconolactone moiety has a larger molecular size, allowing it to exfoliate the skin surface gently without deep, rapid penetration that causes irritation.

Q2: Is this ingredient suitable for people with Rosacea?

Yes. Clinical studies confirm excellent tolerability even for subjects with sensitive skin conditions like rosacea and eczema.

Q3: At what concentration should I use Gluconolactone Peptide?

The recommended dosage for optimal anti-aging and hydration results is between 2% and 5% in the final formulation.

Q4: Does it provide immediate hydration?

Yes, as a Polyhydroxy Acid (PHA), it acts as a powerful humectant that draws water into the epidermis for both immediate and long-term hydration.

Q5: Can it be used in eye creams?

Absolutely. Due to its non-irritating nature and ability to stimulate collagen, it is an ideal active ingredient for the delicate skin around the eyes.

Q6: What are the storage requirements?

It should be stored in a tightly closed container in a dry environment at room temperature to maintain its biological activity.

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