ODM Trifluoroacetyl Tripeptide-2 An Active Peptide Specifically Designed For High-end Eye Care. Suppliers, Exporter

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ODM Trifluoroacetyl Tripeptide-2 An Active Peptide Specifically Designed For High-end Eye Care. Suppliers, Exporter

Products Name	Â Trifluoroacetyl Tripeptide-2
CAS No	Â 64577-63-5
INCI Name	Â Trifluoroacetyl Tripeptide-2
Specification	Â â‰¥95% (HPLC)
Molecular Weight	Â 453.4 g/mol
Chemical Formula	Â Câ‚â‚‰Hâ‚‚â‚…Fâ‚ƒNâ‚„Oâ‚†
Appearance	Â White to off-white crystalline powder
Solubility	Â Soluble in polar organic solvents, slightly soluble in water.

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Product Description

Product Description & Mechanism of Action

MOA (Mechanism of Action)

Trifluoroacetyl Tripeptide-2 is a synthetic, biomimetic peptide specifically engineered for targeted anti-aging, with a primary focus on the delicate periorbital area (around the eyes). Its mechanism of action is sophisticated and multi-faceted, centered on improving dermal-epidermal junction (DEJ) integrity and modulating key structural proteins.

Reinforcement of the Dermal-Epidermal Junction (DEJ): The peptide acts as a signal molecule to help reinforce the DEJ. With age, the DEJ flattens, leading to sagging. This peptide combats this by promoting the organization and strength of the DEJ structures.
Stimulation of Laminin and Collagen IV: It specifically upregulates the synthesis of Laminin V and Collagen Type IV, which "anchors" the epidermis more effectively to the dermis, resulting in a visible lifting and firming effect.
Modulation of Tenascin-X: Influences the expression of Tenascin-X, crucial for maintaining the elasticity and integrity of collagen fibers.

In Vitro Efficacy & Clinical Results

In Vitro Efficacy Data

DEJ Protein Synthesis: Demonstrated a significant increase in the production of key DEJ proteins, including Laminin V (increase of over 200%) and Collagen IV.

Human Fibroblast Activity: Tests showed that the peptide actively promotes fibroblast function, leading to a healthier extracellular matrix.

Clinical Results

Eyelid Lift & Contour Improvement: In clinical trials, application twice daily for 56 days resulted in a measurable lifting of the upper eyelid by an average of 0.8 mm. This translates to a more open, youthful, and alert eye contour.

Reduction in Drooping: Participants showed significant improvement in the appearance of sagging and heavy-looking eyelids, with subjective assessment reporting noticeable tightness and firmness.

Safety & Compatibility

Safety Profile

Designed for high tolerability. It is non-irritating and non-sensitizing to the sensitive skin of the eye area when used at recommended concentrations.

Compatibility

Synergistic Combinations: Works perfectly with Caffeine (puffiness), Hyaluronic Acid (hydration), and Dipeptide-2 (microcirculation).

Stability: Stable under standard cosmetic pH conditions in both aqueous and anhydrous systems.

Recommended Dosage & Formulations

Recommended Usage Level: 5 to 50 ppm (0.0005% - 0.005%). It is an extremely potent ingredient, effective at very low concentrations.

Suitable Formulations:

Eye Serums & Gels
Eye Contour Creams
Targeted Lift & Firming Serums (eyelids, jawline)
Concentrated Ampoules

Summary & Key Selling Points

Targeted Action
Specifically addresses upper eyelid drooping.

Clinically Proven
Measurable lift in millimeters.

Skin Infrastructure
Reinforces the DEJ for lasting firmness.

High Potency
Effective at ppm levels.

Safe & Gentle
Non-irritating for delicate skin.

Marketing Value
"Non-surgical eyelid lift" claim.

Storage

Store in a closed container at a dry place at room temperature.

Animal Testing

Not animal tested.

Vegan

Does not contain animal-derived components.

GMO

GMO-free ingredients used.

Frequently Asked Questions

What is the primary benefit of Trifluoroacetyl Tripeptide-2?

The primary benefit is targeted anti-aging for the eye area, specifically providing a visible "lifting" effect for sagging or drooping upper eyelids.

How does it work at the cellular level?

It acts on the Dermal-Epidermal Junction (DEJ) by stimulating the synthesis of Laminin V and Collagen IV, which strengthens the skin's foundation and prevents sagging.

Is this ingredient clinically proven?

Yes, clinical trials showed a measurable lift of the upper eyelid by an average of 0.8 mm after 56 days of consistent application.

What is the recommended dosage for eye creams?

It is highly potent and recommended at concentrations between 5 to 50 ppm (0.0005% - 0.005%).

Is it safe for use in the sensitive eye area?

Absolutely. It has been tested and proven to be non-irritating and non-sensitizing, making it ideal for the most delicate skin zones.

Can it be combined with other active ingredients?

Yes, it works synergistically with ingredients like Caffeine for dark circles, Hyaluronic Acid for hydration, and other peptides for overall rejuvenation.