Palmitoyl Tripeptide-38 is a biomimetic peptide specifically engineered to target and reinforce the dermal-epidermal junction (DEJ), a critical structure for maintaining skin's youthful architecture and firmness.
Increased DEJ Protein Synthesis: Significantly increased production of Collagen IV (by over 200%), Collagen VII, and Laminin V.
Enhanced Dermal Collagen: Marked upregulation in the synthesis of Collagen I and III by human dermal fibroblasts.
Gene Expression: Positively modulates skin cell gene expression towards a matrix-producing state.
Clinical studies confirm significant anti-aging benefits after 12 weeks of use (3 ppm twice daily):


Palmitoyl Tripeptide-38 is well-tolerated and non-irritating when applied topically at recommended concentrations. It is suitable for all skin types, including sensitive skin.
Synergistic Combinations: Works well with other peptides (e.g., Matrixyl 3000), Hyaluronic Acid, Niacinamide, and Antioxidants (Vitamin C, E).
Formulation Stability: Stable under standard cosmetic pH conditions (pH 4.0 - 7.0) and typical processing temperatures.
A highly potent ingredient effective at very low concentrations.




