Buy What is Tripeptide-41? Benefits for Anti-Aging and Firming Skin Suppliers, Company

Products Name  Tripeptide-41
CAS No  Not publicly assigned or Not Found
INCI Name  Tripeptide-41
Specification  ≥95% (HPLC)
Molecular Weight   340.38 g/mol 
Chemical Formula  C₁₅H₂₄N₄O₅
Appearance   White to off-white powder
Solubility  Soluble in water

Product Description

Product Description

Tripeptide-41 Mechanism
1. Mechanism of Action
Tripeptide-41 is a synthetically engineered bioactive peptide designed to target the extracellular matrix (ECM) and cellular communication pathways.
  • Extracellular Matrix Compaction & Reinforcement: Functions as a matrikine signaling peptide, mimicking natural collagen fragments for repair.
  • Signal Transduction: Binds to Integrins on dermal fibroblasts to trigger intracellular signaling.
  • Upregulation of Key Proteins: Promotes synthesis of Collagen I, III, IV, and Laminin.
  • Overall Effect: Mechanical reinforcement resulting in "tightening" and "lifting" effects, reducing sagging.

Efficacy & Clinical Results

In-Vitro Efficacy

Model: Human Dermal Fibroblasts

  • Collagen Synthesis: ~150% increase in Collagen I production.
  • Laminin Production: Over 200% increase in Laminin 5.
  • Gene Expression: PCR data confirmed upregulation of COL1A1 and LAMC2.

Clinical Results

Study: 12-week, double-blind study (35-65 age group).

  • Skin Firmness: 15% improvement (Cutometry).
  • Wrinkle Depth: 20% reduction recorded via profilometry.
  • Expert Assessment: 85% showed visible lifting on jawline/cheeks.

Safety & Compatibility

Safety Profile
Formulation Compatibility

Safety Profile

Excellent topical safety; non-irritating and non-sensitizing in RIPT testing. Compatible with sensitive skin and biodegradable.

Formulation Stability

  • Solubility: High Water Solubility.
  • pH Range: Stable between 4.0 - 8.0.
  • Combination: Synergetic with Vitamin C, HA, and Niacinamide.

Recommended Usage & Dosage

Usage Guide

Recommended Dosage: 2 - 10 ppm (0.0002% - 0.001%)

Suggested Product Forms: Anti-Aging Serums, Concentrated Face Creams, Eye Contour Creams, Neck Treatments, and Sheet Masks.

Summary & Key Selling Points

Targeted Reinforcement

Compacts dermal ECM.

Clinically Proven

Visible improvements in lifting.

Protein Boost

Stimulates Collagen I, III, IV.

High Potency

Effective at 2-10 ppm.

Skin Friendly

Suitable for all skin types.

Modern Solution

Science-backed anti-aging.

Storage

Dry place at room temp

Animal Testing

Not animal tested

Vegan

No animal components

GMO

No data available

Frequently Asked Questions

Q1: What is the primary function of Tripeptide-41?

A: Tripeptide-41 functions as a matrikine signaling peptide that reinforces the dermal extracellular matrix, leading to visible skin tightening and lifting effects.

Q2: How does Tripeptide-41 affect collagen production?

A: Clinical models show it can increase Collagen I production by approximately 150% and significantly upregulate Collagen III, IV, and Laminin synthesis.

Q3: Is this ingredient safe for sensitive skin?

A: Yes, it has an excellent safety profile, is non-irritating, non-sensitizing, and is composed of skin-friendly amino acids.

Q4: What is the recommended dosage for cosmetic formulations?

A: The recommended usage is between 2 - 10 ppm, with 4 - 5 ppm typically sufficient for significant clinical results.

Q5: Can it be combined with other anti-aging ingredients?

A: Absolutely. It is highly compatible with Hyaluronic Acid, Vitamin C, Niacinamide, and other peptides like Matrixyl™.

Q6: What is the stability and solubility of Tripeptide-41?

A: It features high water solubility and remains stable across a broad pH range of 4.0 to 8.0, making it easy to incorporate into serums and lotions.

Related Products